Article Sidebar

Download
PDF
Statistic
Read Counter : 105 Download : 52

Main Article Content

Abstract

Purpose: This study aims to evaluate the effect of iron tablet supplementation on pregnant women from the first to the third trimester in preventing pregnancy-related anemia. The primary focus is on understanding the dynamics of consumption compliance, maternal perceptions, the effectiveness of health education, as well as environmental factors and accessibility that influence the success of the intervention.


Research Method: This study employed a qualitative approach, based on a systematic literature review of relevant publications from 2018 to 2025. The analysis was conducted thematically to identify consumption patterns, motivations, educational interventions, and their impact on the hemoglobin status of pregnant women.


Results and Discussion: The findings indicate a progressive trend in adherence to iron tablet consumption from the first to the third trimester, with the main barriers being complaints of nausea and gastrointestinal side effects. Positive perceptions of the benefits of iron tablets, along with appropriate social support and education, have been shown to improve adherence. Health education tailored to the stage of pregnancy is more effective in changing behavior. Consistent iron tablet consumption contributes to increased hemoglobin levels and reduces the risk of anemia, as well as pregnancy complications such as preterm birth and low birth weight.


Implications: This study provides original contributions to the development of trimester-based maternal health education strategies and the improvement of iron tablet availability in primary care. The implications include strengthening maternal and child health program policies and involving multiple stakeholders, including families and communities, in supporting the success of interventions.

Keywords

iron tablets pregnancy anemia trimester of pregnancy health education

Article Details

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite
Yahya, F. D., Munawwarah, S., Hasriantirisna, H., & Nanda, K. R. (2025). Qualitative Study on Pregnant Women’s Perceptions of Iron Tablet Administration in Anemia Prevention during the First to Third Trimesters. Advances in Healthcare Research, 3(2), 187–201. https://doi.org/10.60079/ahr.v3i2.537
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX

References

  1. Anato, A., & Reshid, M. (2025). Effect of nutrition education and iron-folic acid supplementation on anemia among pregnant women in Ethiopia: a quasi-experimental study. Scientific Reports, 15(1), 3556. https://doi.org/10.1038/s41598-025-87957-x
  2. Anggraini, D. D. (2018). Faktor predisposisi ibu hamil dan pengaruhnya terhadap kepatuhan mengkonsumsi tablet besi (FE) dan anemia pada ibu hamil. Strada Jurnal Ilmiah Kesehatan, 7(1), 9–22. https://doi.org/10.30994/SJIK.V7I1.141
  3. Banerjee, A., Athalye, S., Shingade, P., Khargekar, V., Mahajan, N., Madkaikar, M., & Khargekar, N. (2024). Efficacy of daily versus intermittent oral iron supplementation for prevention of anaemia among pregnant women: a systematic review and meta-analysis. EClinicalMedicine, 74. https://doi.org/10.1016/j.eclinm.2024.102742
  4. Beard, J. L. (2000). Effectiveness and strategies of iron supplementation during pregnancy123. The American Journal of Clinical Nutrition, 71(5), 1288S–1294S. https://doi.org/https://doi.org/10.1093/ajcn/71.5.1288s
  5. Benjamin, G., Mrema, E. J., Nhumba, N., Wakoli, A. B., & Mwanga, H. H. (2025). Adherence to iron deficiency interventions among pregnant women attending antenatal clinics in Ubungo municipality, Dar es Salaam, Tanzania. Bulletin of the National Research Centre, 49(1), 8. https://doi.org/10.1186/s42269-025-01301-x
  6. Derman, R. J., Bellad, M. B., Somannavar, M. S., Bhandari, S., Mehta, S., Mehta, S., Sharma, D. K., Yogeshkumar, S., Charantimath, U., Patil, A. P., Mallapur, A. A., Ramadurg, U., Sangavi, R., Patil, P. S., Roy, S., Vastrad, P., Shekhar, C., Leiby, B. E., Hartman, R. L., … Boelig, R. C. (2025). Single-dose intravenous iron vs oral iron for treatment of maternal iron deficiency anemia: a randomized clinical trial. American Journal of Obstetrics and Gynecology. https://doi.org/https://doi.org/10.1016/j.ajog.2025.01.037
  7. Detlefs, S. E., Jochum, M. D., Salmanian, B., McKinney, J. R., & Aagaard, K. M. (2022). The impact of response to iron therapy on maternal and neonatal outcomes among pregnant women with anemia. American Journal of Obstetrics & Gynecology MFM, 4(2), 100569. https://doi.org/10.1016/j.ajogmf.2022.100569
  8. Díaz-Torres, S., Díaz-López, A., & Arija, V. (2024). Effect of prenatal iron supplementation adapted to hemoglobin levels in early pregnancy on fetal and neonatal growth—ECLIPSES Study. Nutrients, 16(3), 437. https://doi.org/10.3390/nu16030437
  9. Edeo Berarti, A., Gebrie, M., & Beyene, B. (2023). Adherence to iron folic acid supplementation and associated factors among antenatal CARE attending women in Sire district primary health care units, South-East Ethiopia: A facility based cross-sectional study. International Journal of Africa Nursing Sciences, 18, 100526. https://doi.org/https://doi.org/10.1016/j.ijans.2023.100526
  10. Farias, P. M., Marcelino, G., Santana, L. F., de Almeida, E. B., Guimarães, R. de C. A., Pott, A., Hiane, P. A., & Freitas, K. de C. (2020). Minerals in pregnancy and their impact on child growth and development. Molecules, 25(23), 5630. https://doi.org/10.3390/molecules25235630
  11. Fite, M. B., Roba, K. T., Oljira, L., Tura, A. K., & Yadeta, T. A. (2021). Compliance with Iron and Folic Acid Supplementation (IFAS) and associated factors among pregnant women in Sub-Saharan Africa: A systematic review and meta-analysis. PLoS One, 16(4), e0249789. https://doi.org/10.1371/journal.pone.0249789
  12. Hasriantirisna, H. (2024). Effectiveness of FE Tablet Consumption on Haemoglobin Level Increase Haemoglobin Levels in Pregnant Women. Advances in Healthcare Research, 2(1), 13–22. https://doi.org/10.60079/ahr.v2i1.346
  13. Hidayati, T., Hanifah, I., & Widayati, A. (2024). Pengalaman Kepatuhan Ibu Hamil Dalam Mengkonsumsi Tablet Fe Di Desa Baratan Kecamatan Binakal Kabupaten Bondowoso. Jurnal Keperawatan, 17(2), 69–75. https://doi.org/10.56586/jk.v17i2.364
  14. Ibsen, C. P., Scavenius, C., Frederiksen, K. D., Wonsbek, L., Ammitzbøll, I. L. A., Vojdeman, F. J., Glenthøj, A., Noer, M. C., Lauenborg, J., Mandrup, C. M., & Clausen, T. D. (2025). Impact of second trimester iron deficiency on maternal and infant outcomes: A Danish cohort study. European Journal of Obstetrics & Gynecology and Reproductive Biology, 311, 114004. https://doi.org/https://doi.org/10.1016/j.ejogrb.2025.114004
  15. Kamau, M. W., Mirie, W., & Kimani, S. (2018). Compliance with Iron and folic acid supplementation (IFAS) and associated factors among pregnant women: results from a cross-sectional study in Kiambu County, Kenya. BMC Public Health, 18(1), 580. https://doi.org/10.1186/s12889-018-5437-2
  16. Kinshella, M.-L. W., Moore, S. E., & Elango, R. (2025). Current evidence around key underrepresented women’s health topics in pregnancy and postpartum nutrition: a narrative review. Applied Physiology, Nutrition, and Metabolism, 50, 1–16. https://doi.org/10.1139/apnm-2024-0127
  17. Kirthan, J. P. A., & Somannavar, M. S. (2024). Pathophysiology and management of iron deficiency anaemia in pregnancy: a review. Annals of Hematology, 103(8), 2637–2646. https://doi.org/10.1007/s00277-023-05481-2
  18. McCarthy, E. K., Schneck, D., Basu, S., Xenopoulos-Oddsson, A., McCarthy, F. P., Kiely, M. E., & Georgieff, M. K. (2024). Longitudinal evaluation of iron status during pregnancy: a prospective cohort study in a high-resource setting. The American Journal of Clinical Nutrition, 120(5), 1259–1268. https://doi.org/https://doi.org/10.1016/j.ajcnut.2024.08.010
  19. Mengistu, G. T., Mengistu, B. K., Gudeta, T. G., Terefe, A. B., Habtewold, F. M., Senbeta, M. D., Sori, S. A., & Jiru, H. D. (2022). Magnitude and factors associated with iron supplementation among pregnant women in Southern and Eastern Regions of Ethiopia: Further Analysis of mini demographic and health survey 2019. BMC Nutrition, 8(1), 66. https://doi.org/10.1186/s40795-022-00562-3
  20. Ng’ethe, H. M. (2020). Determinants of Non-Compliance to Iron Folic Acid Supplementation during Pregnancy. A Case Study of Nyeri County, Kenya. KeMU. http://repository.kemu.ac.ke/handle/123456789/928
  21. Nova, D., & Irawati, M. (2021). Hubungan Konsumsi Tablet Fe Pada Ibu Hamil Dengan Kejadian Anemia. Menara Medika, 3(2). https://doi.org/10.31869/MM.V3I2.2531
  22. Pandey, A. K., Gautam, D., Tolani, H., & Neogi, S. B. (2024). Clinical outcome post treatment of anemia in pregnancy with intravenous versus oral iron therapy: a systematic review and meta-analysis. Scientific Reports, 14(1), 179. https://doi.org/10.1038/s41598-023-50234-w
  23. Pasricha, S.-R., Moya, E., Ataíde, R., Mzembe, G., Harding, R., Mwangi, M. N., Zinenani, T., Prang, K.-H., Kaunda, J., Mtambo, O. P. L., Vokhiwa, M., Mhango, G., Mamani-Mategula, E., Fielding, K., Demir, A., Von Dinklage, N., Verhoef, H., McLean, A. R. D., Manda-Taylor, L., … Phiri, K. S. (2025). Ferric carboxymaltose for anemia in late pregnancy: a randomized controlled trial. Nature Medicine, 31(1), 197–206. https://doi.org/10.1038/s41591-024-03385-w
  24. Pasricha, S.-R., Mwangi, M. N., Moya, E., Ataide, R., Mzembe, G., Harding, R., Zinenani, T., Larson, L. M., Demir, A. Y., & Nkhono, W. (2023). Ferric carboxymaltose versus standard-of-care oral iron to treat second-trimester anaemia in Malawian pregnant women: a randomised controlled trial. The Lancet, 401(10388), 1595–1609. https://doi.org/10.1016/S0140-6736(23)00278-7
  25. Rabiatunnisa, R., & Mujahadatuljannah, M. (2024). Analisis Tingkat Kepatuhan Konsumsi Tablet FE pada Ibu Hamil Trimester III di DAS: Analysis of the Level of Compliance with FE Tablet Consumption in III Trimester Pregnant Women in DAS. Jurnal Surya Medika (JSM), 10(2), 236–241. https://doi.org/10.33084/jsm.v10i2.7748
  26. Sandy, D. M., & Sulistyorini, S. (2024). Edukasi Pentingnya Konsumsi Tablet Fe Bagi Ibu Hamil: Education On The Importance of Fe Tablets Consumption For Pregnant Women. Jurnal Abdimas Pamenang, 2(1), 55–60. https://doi.org/10.53599/jap.v2i1.190
  27. Sarah, S., & Irianto, I. (2018). Pengaruh tingkat kepatuhan minum tablet Fe terhadap kejadian anemia pada ibu hamil trimester III di Puskesmas Pejeruk tahun 2017. Jurnal Kedokteran YARSI, 26(2), 75–85. https://doi.org/10.33476/jky.v26i2.392
  28. Sharawat, I. K., Panda, P. K., Choudhary, S., Pradhan, P., Malik, V. S., & Singh, M. (2024). Efficacy of different doses of daily prophylactic iron supplementation in pregnant women: A systematic review and meta-analysis. Clinical Nutrition ESPEN, 64, 122–132. https://doi.org/https://doi.org/10.1016/j.clnesp.2024.09.019
  29. Solomon, Y., Sema, A., & Menberu, T. (2021). Adherence and associated factors to iron and folic acid supplementation among pregnant women attending antenatal care in public hospitals of Dire Dawa, Eastern Ethiopia. European Journal of Midwifery, 5, 35. https://doi.org/10.18332/ejm/138595
  30. Susiloningtyas, I. (2012). Pemberian zat besi (Fe) dalam Kehamilan. Majalah Ilmiah Sultan Agung, 50(128), 73–99.
  31. Taye, M., Mohammed, T., Taye, W., Glagn, M., & Yihune, M. (2025). Compliance with iron-folate supplementation among pregnant women in Southern Ethiopia: a multi-center cross-sectional study. Reproductive Health, 22(1), 22. https://doi.org/10.1186/s12978-025-01944-z
  32. Traore, S. S., Bo, Y., Kou, G., & Lyu, Q. (2023). Iron supplementation and deworming during pregnancy reduces the risk of anemia and stunting in infants less than 2 years of age: a study from Sub-Saharan Africa. BMC Pregnancy and Childbirth, 23(1), 63. https://doi.org/10.1186/s12884-023-05399-7
  33. Wulandari, R. (2018). Pengaruh kepatuhan ibu hamil dalam mengkonsumsi tablet fe terhadap kadar hb ibu hamil trimester iii. Jurnal Ilmiah Kebidanan Indonesia, 8(02), 58–69. https://doi.org/10.33221/JIKI.V8I02.146