Main Article Content
Abstract
Purpose: This study explores the relationship between environmental factors—such as clean water supply, fecal disposal, waste treatment, household waste security, and household drinking water treatment—and the incidence of typhoid fever in Barru District, South Sulawesi. The hypothesis suggests that inadequate environmental sanitation and poor water supply are major contributors to the spread of typhoid fever.
Research Design and Methodology: The research utilized a cross-sectional observational design, focusing on 80 Barru Regional General Hospital patients. Respondents were selected through purposive sampling based on specific criteria. Data were gathered through direct observations, structured interviews, and hospital medical records. The Chi-Square test was used to analyze the relationships between the identified variables.
Findings and Discussion: The findings indicate a significant relationship between clean water supply and household waste security with typhoid fever incidence. Respondents lacking access to clean water and proper waste management practices showed a higher risk of infection. However, no significant associations were observed between typhoid fever incidence and factors like fecal disposal, waste treatment, or household drinking water treatment.
Implications: These results suggest that policy interventions aimed at improving water supply and waste management practices at the community level could effectively reduce the incidence of typhoid fever. Future research should investigate the interaction between these environmental factors and individual behaviors, extending the study to other regions for a more comprehensive understanding.
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References
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References
Ajibola, O., Mshelia, M. B., Gulumbe, B. H., & Eze, A. A. (2018). Typhoid fever diagnosis in endemic countries: a clog in the wheel of progress? Medicina, 54(2), 23. https://doi.org/10.3390/medicina54020023
Arif, M. S., Raza, A., Rafiq, M., Bibi, M., Fayyaz, R., Naz, M., & Javed, U. (2019). A reliable stochastic numerical analysis for typhoid fever incorporating with protection against infection. Comput. Mater. Continua, 59(3), 787–804. http://www.techscience.com/cmc
Balaji, V., Kapil, A., Shastri, J., Pragasam, A. K., Gole, G., Choudhari, S., Kang, G., & John, J. (2018). Longitudinal typhoid fever trends in India from 2000 to 2015. The American Journal of Tropical Medicine and Hygiene, 99(3 Suppl), 34. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128365/
Chatham-Stephens, K., Medalla, F., Hughes, M., Appiah, G. D., Aubert, R. D., Caidi, H., Angelo, K. M., Walker, A. T., Hatley, N., & Masani, S. (2019). Emergence of extensively drug-resistant Salmonella Typhi infections among travelers to or from Pakistan—United States, 2016–2018. Morbidity and Mortality Weekly Report, 68(1), 11. https://doi.org/10.15585%2Fmmwr.mm6801a3
Crump, J. A. (2019). Progress in typhoid fever epidemiology. Clinical Infectious Diseases, 68(Supplement_1), S4–S9. https://doi.org/10.1093/cid/ciy846
Gibani, M. M., Jones, E., Barton, A., Jin, C., Meek, J., Camara, S., Galal, U., Heinz, E., Rosenberg-Hasson, Y., & Obermoser, G. (2019). Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model. Nature Medicine, 25(7), 1082–1088. https://www.nature.com/articles/s41591-019-0505-4
Habte, L., Tadesse, E., Ferede, G., & Amsalu, A. (2018). Typhoid fever: clinical presentation and associated factors in febrile patients visiting Shashemene Referral Hospital, southern Ethiopia. BMC Research Notes, 11(1), 1–6. https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-018-3713-y
Kim, J.-H., Im, J., Parajulee, P., Holm, M., Cruz Espinoza, L. M., Poudyal, N., Mogeni, O. D., & Marks, F. (2019). A systematic review of typhoid fever occurrence in Africa. Clinical Infectious Diseases, 69(Supplement_6), S492–S498. https://doi.org/10.1093/cid/ciz525
Levine, M. M., & Simon, R. (2018). The gathering storm: is untreatable typhoid fever on the way? MBio, 9(2). https://doi.org/10.1128/mBio.00482-18
Marchello, C. S., Hong, C. Y., & Crump, J. A. (2019). Global typhoid fever incidence: a systematic review and meta-analysis. Clinical Infectious Diseases, 68(Supplement_2), S105–S116. https://doi.org/10.1093/cid/ciy1094
Milligan, R., Paul, M., Richardson, M., & Neuberger, A. (2018). Vaccines for preventing typhoid fever. Cochrane Database of Systematic Reviews, 5. https://doi.org/10.1002/14651858.CD001261.pub3
Mogasale, V. V, Ramani, E., Mogasale, V., Park, J. Y., & Wierzba, T. F. (2018). Estimating typhoid fever risk associated with lack of access to safe water: a systematic literature review. Journal of Environmental and Public Health, 2018. https://doi.org/10.1155/2018/9589208
Murphy, J. L., Kahler, A. M., Nansubuga, I., Nanyunja, E. M., Kaplan, B., Jothikumar, N., Routh, J., Gómez, G. A., Mintz, E. D., & Hill, V. R. (2017). Environmental survey of drinking water sources in Kampala, Uganda, during a typhoid fever outbreak. Applied and Environmental Microbiology, 83(23), e01706-17. https://doi.org/10.1128/AEM.01706-17
Organization, W. H. (2019). Typhoid vaccines: WHO position paper, March 2018–Recommendations. Vaccine, 37(2), 214–216. https://doi.org/10.1016/j.vaccine.2018.04.022
Park, S. E., Pham, D. T., Boinett, C., Wong, V. K., Pak, G. D., Panzner, U., Espinoza, L. M. C., von Kalckreuth, V., Im, J., & Schütt-Gerowitt, H. (2018). The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa. Nature Communications, 9(1), 1–10. https://www.nature.com/articles/s41467-018-07370-z
Prasad, N., Jenkins, A. P., Naucukidi, L., Rosa, V., Sahu-Khan, A., Kama, M., Jenkins, K. M., Jenney, A. W. J., Jack, S. J., & Saha, D. (2018). Epidemiology and risk factors for typhoid fever in Central Division, Fiji, 2014–2017: a case-control study. PLoS Neglected Tropical Diseases, 12(6), e0006571. https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0006571
Radhakrishnan, A., Als, D., Mintz, E. D., Crump, J. A., Stanaway, J., Breiman, R. F., & Bhutta, Z. A. (2018). Introductory article on global burden and epidemiology of typhoid fever. The American Journal of Tropical Medicine and Hygiene, 99(3 Suppl), 4. https://doi.org/10.4269%2Fajtmh.18-0032
Rasheed, M. K., Hasan, S. S., & Ahmed, S. I. (2019). Extensively drug-resistant typhoid fever in Pakistan. The Lancet Infectious Diseases, 19(3), 242–243. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(19)30051-9/fulltext
Shaikh, A. S., & Nisar, K. S. (2019). Transmission dynamics of fractional order Typhoid fever model using Caputo–Fabrizio operator. Chaos, Solitons & Fractals, 128, 355–365. https://doi.org/10.1016/j.chaos.2019.08.012
Veeraraghavan, B., Pragasam, A. K., Bakthavatchalam, Y. D., & Ralph, R. (2018). Typhoid fever: issues in laboratory detection, treatment options & concerns in management in developing countries. Future Science OA, 4(6), FSO312. https://doi.org/10.4155/fsoa-2018-0003
